Abstract
BACKGROUND:
Bronchiolitisobliteranssyndrome(BOS)afterallogeneichematopoieticstemcelltransplantation(HSCT)iscurrentlytreatedwithsystemiccorticosteroidsdespitepoorefficacyandsideeffects.Thisstudyinvestigatedthetherapeuticeffectofbudesonide/formoterol,montelukastandn-acetylcysteine,whicharesuggestedastreatmentoptionsforBOSafterHSCT.
METHODS:
AfterdiagnosisofBOS,61patientsweretreatedwithbudesonide/formoterol,montelukastandn-acetylcysteinefor3months.PulmonaryfunctiontestandCOPDassessmenttest(CAT)wereperformedbeforeandafterthe鍖椾含鎬庝箞娌荤枟鐧界櫆椋?鍖椾含鏈濂界櫧鐧滈鍖婚櫌淇℃伅